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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8e1c57910327cc53e77f9f1a1d3d9e77a8b6e03767df322e5a59d925e1401339' 
  AND token = 'lw+avlHq1nZDpwnBjVil5aP5up0rNbfHp8yzBCaqJRo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}