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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'adb74d9a903e983eada58029d088346626724734c21f8f64199941681b0a0f77' 
  AND token = 'GdYzytvqgNUmR2qLDaDjPhb20szTkqqteD6OMz/0Uw0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}