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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b44ce88d96e5a05280cf56d0f135ab6602d6de7577613558aa2a5acb14b869b' 
  AND token = 'HJGS5p/76zYHXLeU9CJrNuMthsvLR4/tN8BO6RVcqao=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}