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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3fe63a4380fbada3e02b7d12a7affd7c53da694108d32e36909f82cec853e7f3' 
  AND token = 'OTE3FQV03Yb3zPS981cxodcs+zCUlnTG8uEYWpVj0Sc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00082

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}