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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '241bbc5af4eddf157bb6fce6e7d6d2b098c5a33240c774e432d82883e69edde1' 
  AND token = 'UwVpGV942vrTvrgxrxP0fNXkUzSY8Xvf/Ui/j8l/vLA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}