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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1f988cdc55e49bf75258d2eda0c323f4cb4e18c3d73694a4687a094ea4a02d0d' 
  AND token = 'IHO6r3h9RiziBErx6wEZGJJVBb1hcwHIzDxwJ1cIw0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}