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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd860e57d03182080356ca02a940c97b89d943f5a82498da9f58a20904c23fec2' 
  AND token = 'lxLu3dD3np5F2z8FGSiV0le6qYi/OBtCGhjlV74Qjlo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00076

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}