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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8190d00ff0b8264cee379d3791d26f068b89d075e3f3a1a807645f72ae2dbcb4' 
  AND token = 'mC76+l8490fG/I5dpJhh06VH5tHhOUXfqNt9MMPI/Xg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}