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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'fef27bd96a926fa4ef2a4f3b229d689c25ad7591d27f7ec0b382e1772985602c' 
  AND token = 'w7l2vDBktaTuiFEUon++QPSfm99q8RpZR+YcqreOVsg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}