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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bd94f8c170a7a20910af7b58d412b9eafdf3a839a4feb45b20cbbdeca1b30e12' 
  AND token = 'Y9VvLPHQ/BORp6EKq/I65kpyfBpXlbEioUzpuCmWfg0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}