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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f15bb55d1fa5a828ce1d336ac900fca4fb9525a0b44a44a497565b605f6a0a8' 
  AND token = 'M7XqD9WnD2TQa8SlQCROGECu41fez+7Ahm0xj5nbb9o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}