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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cf869122e3b5c35179d2640916788bd32943eb5a9fa7fbcef1d04a2500ff8f88' 
  AND token = '+fcK+cUjLJUJ92zfbF8GUVFvDOFz8HJ1+mePB7B10B8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00077

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}