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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8a91c78dc4aad55723007c22868a5a83fb9a85b0603208c645f6d1960d6abc2f' 
  AND token = 'JnvTfbIvVaTl5D1Idtkk6MfuI7OzZSWtyoskKYMO8BM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}