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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3b72bc44efdf7d344c0cfa04d89962292557b8aecd785887908ab0b72a2d4957' 
  AND token = 'O8fFpV6osMnmTalFi4f8IBhFuTGatLYTX9uDiMQWCDQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}