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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef442de141c8bcc7f55e0fd1d9d6bd4bfa589492f5b37a3de373805cccfc74e5' 
  AND token = 'lXedJ/yzAP69TFdMRZZ3siaCC2DEiEh421fDuUEt+3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}