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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ea53cf822a04f4d9f4c427a6fbb2efd36da0666753417999f4648605171da855' 
  AND token = 'GApq9804DgVsFdYn7ag0pGe3zARQbntLk9dzOFR4nz0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00068

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}