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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'cfe62e1784e94a776cd26180658922677ab10eab4d95a6434a0a35a737625a36' 
  AND token = 'YtE6/5rFtdPEa8j85tbSZf0b9aAFuUSQoxDQ0XXPdGQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}