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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '320366fc129dead2aaf25ac5bf2f7c77fc9b857a0bca4d14f41af6deaab5d966' 
  AND token = 'JMMMK/XkzxH7+5O3ZVVRWt04kcM9/6D1yVrK4h5jlbo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}