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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2a1a394e4802b87a463004c4f110b768e4cde0efd70000f3bf4da151c6136f52' 
  AND token = 'LU8eyklxr2/xdH7rxEBcDrt90s9+vqCYgbq4x2+/Hww=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}