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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b51086d08d91307904f1b0a036da14f4f8b3c3f9c0e73595807be1f5194ad5a0' 
  AND token = '5kPSRD2t+BiOsmZ2j116fIxYL4wold7od+Ku4S9qbWw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}