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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b36743aca57dd9a9bc66912e3163fa76e3191833e044b527d8cf516f8e4e958d' 
  AND token = 'fIb+l0YEIzdWge6uDoEU+0SaiqNC4yX/nkmEgJ/Jcyo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}