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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '422a5d7b67c45470f7f191a53a04082d4bb5e399c357d143cf7dcbd22bc6cae6' 
  AND token = 'ThHTnGjhNSyF8ZVo5SioTqVq58HKbvyNfjuBe2PsdPo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00014

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}