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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a4a5e1584b88dbbb52dc639c31765d157f93e4b4aa644645decc81d5eacc9e1' 
  AND token = 'TIoKc4d1floP7eZpEknwOyWRAsZwEe8LY3UEh1lg6hQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}