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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2540c95a17f3f8428fc82493254ac5bf1a505e5a9f51ac92c0889808dd2baafd' 
  AND token = 'zb3rSSgqGF6EC5WR2FohJvOTke3KFNsGDCMuqqRP2jI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}