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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7ac69a263091555f5f1a2602780da6b9a2d7e65859e42a8f5ba7a61467d7e89d' 
  AND token = 'swHGhWPMBWe24A2JApiWC8bnoGkZbx3x2XDFBZPOEqE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}