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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5cdaf962bce4a0bd904a7023b541606dad2ccfaef405a8b2771f63053ca1d0f0' 
  AND token = 'X2wGe3hAxR6+kdDrHGSj+SNAsWBweLvRUfA+QEioWtc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}