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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e680f758859d1bf37f58631237f0eb1a6b65ce9bdd4f6ee0d1116f9ee9d7850' 
  AND token = 'XG+7zIcaMMe4yvpDAzlQFK3tMipkNTzeMZ3EfcWCyfQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00098

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}