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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e24928e19666c361fc5ad89a03a61bef137f9f1afc6103cc344a8b27d5ed2673' 
  AND token = 'mfSPk5zOOLAgnUjdSsY8A1WgPpyLibxw0nN9bEUPpoo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00073

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}