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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6f759e420e1da157dccf2dc99de4ab35518caceee0d0f2ef1016d0dd3a062a4c' 
  AND token = 'lPXkg82UH1pwcisAGU2mpt5SbpwQB7FGIGtIW6Q+HOQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}