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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e77705f66a168db166b88f92a0cf5ca31e64a702f2cf72ac576cc1856090ece4' 
  AND token = 'PX6xG+E1I9hAWJEiG0jDc465NTGC2g+qh8cbZtTsABg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}