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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a7187a3a4928666a2e6f5cafcb5f55f9e569f4e7d2d6fe6bec554a346c2a4810' 
  AND token = 'hpTS1hdUIgbwDbeUK4vCp16H3ybT+ucZtVu1FSCRLVs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}