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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c0d24c71d29e6fc4ec5abd5d178bb3923b4376c65986d26c302881bce4f3725' 
  AND token = 'VR2v8dC2yRQonte5SGyyYaqR2gIaZq5eUhgwDtA1cpA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00078

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}