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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d5a5633e7b3051380a47d53cddb5089f4d894cc79ea9fd7f5a2500cfd603f06' 
  AND token = 'Ga5xMBKL93AAGxCIoD01wG9l+NgkN+JPOsqVjMPbNyY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}