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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6d6d75d768dbf2cff48d3921c1672f61676b1c8553fccd92ca0c164972dd3b20' 
  AND token = 'z1JxG80ugakApWFfYKZ97PzUt2MsIPFFcmPV6Gxf74Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}