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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '96dd3002f26bc18d67393761b94915e08a75c07d3a4a8c6fb630ae29e65e4222' 
  AND token = '+5OHs/cd8TWC1MHBmEEtUQAqdtwXARKUdHCMAWKEGPE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00066

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}