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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f16151d5be6c9ee6fa85825524638cb4be812870877cd36d19c93f2d12592c28' 
  AND token = '6v0PmJaOlz832PSX00NJUkizFywgt070tRaNSccvYD0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}