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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b0e8792aa570e8c443dcdf7eb9dfba5c17e366b50629842cd20acff94b8fd8b' 
  AND token = 'Jq1qtNTXI1YreN6+RNSN4ZKfJ9u3YzNrkG0A3qoBzuE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}