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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd146f6aeb6edaed34153327d0fb77cb6eccc2b46fb7a3a7a91e690f1f29edcce' 
  AND token = 'miZM0EZLEEppSHGz7kHNLEKFG+rAGU8VEbBl1E9MZIE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}