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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b28e1ee27b5b13a87932f7c12eb21f244b380ae9d2c7fc3f08d8056750991173' 
  AND token = 'MFBf8s/Nt5MF7wMGf+mG4+j4m4eOzQB27IZ9Bn9CEpw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}