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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7de78bd386c6c31ba1c2adf592143ada86803fb5e0a1db2adb56b65232ee3a45' 
  AND token = 'Y/AdSjJTPhLpsYH/bG0I53tr5y/UOj7b4NtsnaXNb+Y=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00080

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}