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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd3e348a94121d927fcddaf6a168e26ad86f8cde228acc34b8daac76741404868' 
  AND token = 'it7rCaB6f7aoZoI3JfIdCXpXvzNIBCtapYG3bIZNut0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}