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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd1d95bdea25a8d7525d82907fd7c1be82e190207b18db37dd4159a0d1b440e51' 
  AND token = 't8zVJvZsj7zGzje+pJY8k0USLhe4aYYzDrQSGbnhRNY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00074

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}