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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e99328aa1cb1eb73256fbda6a89125b47d6cf8b4d9215e1f9f39a77fecf331e0' 
  AND token = 'yoS0XBtFYU/B6ALA7z+MMefsAvkMpyXSn/Tjz+3L+P0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}