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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82f3c46a13f2b7b0ba649216a5affd6f201743abdbe3b36cb145f7db142322a2' 
  AND token = 'Ixfr2Fivj3t0P/6ZUqn0f8Jf0yl29F3g5qMUoRa6h60=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00013

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}