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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22e970c675c1bb547f19b4ffdf92c603eaf10c8aa567d42e4ba8dc4b934ba668' 
  AND token = 'xrsQtv5i3jUrjgcevySkIjCbaR2OD4Qh+0OQkk0Fjrw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}