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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8fab5c6ad16a13248dd562d8bdd4065b0b91445e8f2cab6d2ede578500b0b566' 
  AND token = 'oKsYxzieV4x+CRShIZp2jyFgSgs05N97KdEQBVTSXkM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}