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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de47a3a5637246bc1be5f21cdd0a84dc55e2ad33a67070ff023b1b56f8943c7b' 
  AND token = 'dImN5/q4SEKXUMMxUDbuyL+DD4bi6BRS2oI1lcSHPUY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}