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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8398b856cd9188ff20cd8e6164eff81e90b11130e13793285258dccc80057963' 
  AND token = '6mjy0WP1UxmnVZwFwzYyaM8xVm6oBgE1wH1XKS2WaGw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}