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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2af72ef7ad221f1510a159e729ed992fdce5cde864fb5ca0f1e67da095a86624' 
  AND token = '3BjW3iL9BP+LEq4LyLgV8n+pu21rE7FKRCM3arAH0Jo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}