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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbe8286a85be2feef7f44e6aca116c6647f71dcd7506c3f4345b6a524e6304b2' 
  AND token = 'E/Py2jookCZW51Fu5RPBmAgcmSabsdH+pjvPonguXz4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}